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Pancreatic profile is blood tests that can be used to diagnose diseases of the pancreas, but not only. The pancreatic profile is also helpful in diagnosing liver and kidney diseases, and even diabetes. In addition, the pancreatic profile allows you to monitor the treatment of pancreatic diseases. Check what are the indications for a pancreatic profile, what are the standards and how to interpret the test results.

Pancreatic profileare blood and urine tests that allow you to assess the work of the pancreas, an organ involved in digestive processes, and an important gland responsible for insulin secretion, though not only. The pancreatic profile also allows you to answer the question of the condition of, among others, liver or kidneys.

The pancreatic profile includes the assessment of amylase (blood and urine), glucose and lipase levels.

What are the indications for a pancreatic profile?

The indications for a pancreatic profile are symptoms such as epigastric pain radiating to the lumbar region, as well as fever, nausea and vomiting, as they indicate, among others, pancreatic diseases.

The pancreatic profile can also be made to monitor the treatment of pancreatic diseases.

Amylaza

Amylaseis an enzyme produced, inter alia, in through the pancreas, breaking down polysaccharides into simple sugars, which are then absorbed into the gastrointestinal tract.Amylase levels are measured in the blood and urine . In the latter case, it is enough to urinate (from the middle stream) in the morning to a sterile container. You should first take care of the hygiene of intimate places.

Elevated blood amylase levelsover 1150 U / lsuggest acute pancreatitis. Then the amylase norm in the urine is exceeded 3 to 20 times.

Blood concentration in the range575-1150 U / lmay be due to, inter alia, o:

  • gallstone disease,
  • urolithiasis of the pancreatic ducts,
  • gastric ulcer perforation,
  • duodenum.

In turn, too low amylase levels indicate, among others, for very extensive damage to the pancreas (e.g. necrotizing pancreatitis) or serious liver damage.

CHECK>>Pancreatic pain - what can it mean? Causes of pancreatic pain Important

Pancreatic profile - norms

  • Amylase- 25-125 U / I, but in the elderly the level may be much higher - 20-160 U / l (in the blood); 10-490 U / I in urine
  • Lipaza- should not exceed the level of 150.0 U / l
  • Glucose- for adults - 3.9-6.4 mmol / l, newborns - 2.8-4.4 mmol / l, children 3.9-58 mmol / l

Lipaza

Pancreatic lipaseis an enzyme that breaks down fats, specifically food triglycerides, into fatty acids and glycerol. Lipase is also produced by the pancreas, but in an inactive form. Only after reaching the duodenum, lipase transforms into its active form, i.e. ready for digestion.Lipase does not pass into the urine , therefore its concentration can only be assessed with a blood test.

A significantly elevated level of pancreatic lipase, usually 5 or 10 times the normal level, indicates acute pancreatitis. If a sharp rise in blood lipase levels occurs within 24-48 hours of the onset of acute symptoms, and then declines after about 5-7 days, you can be sure of acute pancreatitis.Elevated levels may also suggest pancreatic cancer.

Reduction in lipase levels may indicate chronic pancreatic damage (e.g. in the course of cystic fibrosis). Low lipase levels are common in diabetes.

Read also: What irritates the pancreas and what diseases attack it most often?

Glucose

Glucoseis sugar whose levels in the body are regulated by the pancreatic hormone insulin.

The increase in blood glucose levels may be due to, inter alia, o acute or chronic pancreatitis or cancer of this organ of the pancreas.

A drop in your glucose level can include, but is not limited to:

  • thyroid hormone deficiency,
  • liver damage,
  • Hormonal insufficiency of the pituitary gland.

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