Troponins are contractile proteins of striated muscles (skeletal and heart muscle), in other words, these proteins are a component of myocytes, or muscle cells, and are essential for proper muscle contraction. Troponin levels are measured in people with chest pain, especially at risk of a heart attack (hypertension, diabetes, obesity). Troponin increases for 3 hours after a heart attack.

Contents:

    1. Troponins - research and growth
    2. Troponiny - standard
    3. Troponins in a heart attack
    4. Troponins and other diseases
    5. Troponins - preparation for the test, result

Troponinsare muscle contractile proteins found in skeletal and cardiac muscles. Cardiac troponins are part of the heart muscle cells (cardiomyocytes) and are essential for its proper contraction.

Troponins can be divided into:

      • troponin I (cTnI),
      • troponin T (cTnT),
      • troponin C (cTnC).

So far, the determination of troponins in the blood test indicated a heart attack. Myocardial infarction is indicated by an increase in troponin levels above the 99th percentile and comorbid chest pain and changes in ECG.

Troponins - research and growth

The increase in the concentration of troponin I and T occurs after a heart attack. Troponin T reaches the maximum concentration after 12-24. hours after a myocardial infarction, then it lasts for 48 hours and its concentration decreases - it lasts from 10 to 14 days. Troponin I, on the other hand, has a lower peak concentration and remains in the blood for up to a week.

troponins-norma ">Troponins - norma

It is believed that blood levels of troponins should be zero. Very sensitive tests detect traces of troponins in completely he althy people.

Troponins in a heart attack

The blood troponin test is used to diagnose a recent heart attack, including the so-called micro infarction. In the diagnosis of myocardial infarction, in addition to the troponin concentration, the ECG is also taken into account, including characteristic changes and the presence of typical angina. Only the presence of elevated troponins and one of the other two criteria enables diagnosisheart attack.

Troponins and other diseases

Increased levels of troponins are also associated with other disease syndromes, such as:

      • pulmonary embolism and the accompanying overload of the right ventricle,
      • atrial fibrillation and other arrhythmias,
      • pericarditis, myocarditis,
      • acute and severe congestive heart failure,
      • sepsis,
      • use of cardiotoxic drugs (e.g. adriamycin, doxorubicin, 5-fluorouracil),
      • heart trauma, incl. during cardiac surgery, coronary angioplasty, ablation and cardioversion,
      • chronic renal failure,
      • severe burns,
      • acute respiratory failure,
      • extreme physical exertion,
      • subarachnoid haemorrhage,
      • hypothyroidism,
      • shock,
      • burn,
      • myocardial infiltration in the course of other diseases, e.g. sarcoidosis, haemochromatosis.

Troponins - preparation for the test, result

The troponin test involves taking a blood sample from a vein in the arm. It does not require special preparation from the patient. The examination is usually performed urgently. There are no contraindications for the test. The waiting time for the result is about an hour.

Category:

Research