Fibrinogen is called the first coagulation factor. It is a blood plasma protein produced in the liver. Check what are the fibrinogen standards in a biochemical test and what may be evidenced by an elevated or too low fibrinogen result.
Fibrinogen , the level of which is checked during blood chemistry, is involved in the blood clotting process and is involved in the production of the clot. Measurement of the fibrinogen level is, among others performed as an auxiliary test in the diagnosis of disseminated intravascular coagulation (DIC), including PT, aPTT, platelet and d-dimer counts, and fibrin degradation products (FDP).
Fibrinogen: norms in biochemical research
- 200-500 mg / dl (2-5) g / l)
Increased fibrinogen
Increased fibrinogen results are observed during pregnancy and menstruation, and this is normal, physiological.
In other situations, elevated levels of fibrinogen may indicate acute inflammation in nephrotic syndrome and cancers (leukemia, Hodgkin's disease, or bronchial carcinoma).
Fibrinogen Results Below Normal
Fibrinogen values below normal in blood biochemistry may result from hereditary fibrinogen deficiency, after severe surgery and in situations of excessive fibrinogen consumption due to cancer, sepsis, liver cirrhosis or haemolysis - hemoglobin penetration into plasma caused by erythrocyte breakdown.
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