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Carbon monoxide poisoning can be detected by performing a blood test for carboxyhemoglobin. Carboxyhemoglobin is a biomarker of CO exposure. People suspected of having carbon monoxide poisoning should be examined quickly. Blood levels of more than 70% carboxyhemoglobin mean irreversible changes in the brain as a result of hypoxia, and consequently death.

People suspected of carbon monoxide poisoning should have blood carboxyhemoglobin tested as soon as possible, which is a biomarker of CO exposure. There is no close correlation between the result of this study and the severity of the clinical condition. The prognosis depends on the duration of a person's stay in the poisonous atmosphere rather than the concentration of carbon monoxide in the breathing air.

Blood carboxyhemoglobin levels above 70% indicate irreversible changes in the brain as a result of hypoxia and death.

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