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Hello, I have a question. Both my parents are dead, the cause was cancer - my mother has Hodgkin's lymph nodes, my father has a malignant lymphoma in the head. I am 41 years old and I live abroad, I would like to know what is the probability of getting cancer and what should I do? Is BRCA1 research enough? Thank you and waiting for a reply.
As I mentioned before, when answering other people's questions, for the proper assessment of a person's cancer risk and for the development of individual preventive recommendations, collect a detailedgenetic interviewand analyze the available medical documentation . The age at which relatives (including distant ones) developed cancer is important, as well as the results of histopathological examinations and the he alth condition of the person seeking genetic counseling (some diseases, regardless of the family history, increase the risk of developing cancer).
OptimallyGenetic adviceshould be provided by a specialist in clinical genetics with experience in oncogenetics. During the consultation, the indications for genetic tests will also be discussed. Mutations in the BRCA1 gene predispose to the development of breast, ovarian and prostate cancer to the greatest extent. Of course, mutation carriers may also suffer from other neoplasms. Depending on the spectrum of cancers in the family, a genetic specialist will determine the validity of testing individual genes whose mutations increase the risk of cancer.
Remember that our expert's answer is informative and will not replace a visit to the doctor.
Krystyna SpodarKrystyna Spodar - specialist in the field of clinical genetics at NZOZ Genomed, ul. Ponczowa 12, 02-971 Warsaw, www.nzoz.genomed.pl, e-mail: [email protected]
The expert answers questions about genetic diseases and congenital malformations, inheritance, and prenatal diagnosis.
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