Erytroplasia Queyrata, or red keratosis, is a cancer of the mucous membranes, a form of pre-invasive squamous cell carcinoma (carcinoma in situ) of the skin. Queyrat erythroplasia most often occurs on the glans in uncircumcised men, more rarely on the vulva or vagina, very rarely on the oral or anal mucosa. What are the causes and symptoms of Queyrat erythroplasia? What is the treatment?

Queyrata erythroplasia , otherwisered keratosis , is a neoplastic lesion limited only to the mucous membranes. After many years, malignant skin cancer can develop on its basis. Research shows that Queyrat erythroplasia can cause skin malignancy in only 10 percent of cases. Queyrat erythroplasia is a variant of Bowen's disease, which is a pre-invasive skin cancer.

Queyrat erythroplasia: causes and risk factors

Factors that increase the risk of developing Queyrat erythroplasia are viral infections, especially human papillomavirus (HPV type 16, 18, 31, 33, 35) and herpes simplex virus.

Disease can also be the result of chronic inflammation, the presence of foreskin gland secretions, insufficient hygiene, and physical factors such as heat, chronic irritation, and trauma.

Queyrat erythroplasia: symptoms

ErytroplasjiQueyrata has the form of changes which:

The disease most often develops in uncircumcised men with an average age of 51 years

  • they have a bright red color
  • have a flat, shiny, slightly damp surface
  • are clearly demarcated from the surroundings
  • are singular or plural
  • are most often located on the glans and foreskin in men and on the mucous membranes of the labia in women (less often)

Accompanying symptoms are redness and swelling of the glans or labia. You may also experience penile pain, itching, and problems with passing urine.

Erythroplasia Queyrata - diagnosis

In order to diagnose the disease, a histopathological examination is performed.

Erytroplasia Queyrata - treatment

There are many treatments for Queyrat erythroplasia, including electric current coagulation,irradiation with X-rays, topical treatment with 5-fluorouracil, imiquimod. Therapy may also include cold treatment, photodynamic therapy (PDT), CO laser2 .

Category:

Oncology