Bacterial lysates are prescription drugs that are used to prevent respiratory infections. It is a type of oral vaccine that contains killed bacteria or their fragments. Bacterial lysates most often include streptococci, staphylococci, Haemophilus influenzae, Klebsiella and Moraxella catarrhalis. Who can benefit the most from bacterial lysates?
Bacterial lysatesorprescription oral vaccinesare one of the best-studied groups of drugs that may play a role in preventing systemic infections respiratory system. Bacterial lysates contain killed bacterial cells (or their cell components), most often isolated from the respiratory tract, such as streptococci (e.g. Streptococcus pneumoniae), Staphylococcus aureus, Haemophilus influenzae, Klebsiella and Moraxella catarrhalis.
How do bacterial lysates work?
These preparations are supposed to strengthen immunity by stimulating cells of the immune system, which are grouped in lymph nodes in the gastrointestinal mucosa. Unlike conventional vaccines, they are administered orally.
Are bacterial lysates effective?
The fact that the mechanical lysate of bacteria by 30-40 percent. reduces the incidence of respiratory tract infections in children and adults, confirmed a meta-analysis of 15 studies, which was published in 2012 in Pulmonary Pharmacology and Therapeutics. Research is also underway on its use in the prevention of exacerbations of chronic obstructive pulmonary disease (COPD), which appear as a result of respiratory tract infections. According to the researchers, the fact that bacterial lysates can be effective in preventing infections also caused by viruses is due to the fact that microbes have certain repetitive molecular motifs that are recognized by the cells of our immune system.
When is it worth reaching for bacterial lysates?
Bacterial lysates are medications prescribed by a doctor on a prescription. Based on the test results, they are especially recommended for children who have respiratory tract infections more than 3 times a year. In addition, in order to prepare the body as well as possible before the period of autumn and winter infections, it is worth taking a therapystart already in summer. Bacterial lysates can also be used in adults with recurrent respiratory infections. The decision to prescribe them must be made individually by the doctor after discussing the therapy with the patient.
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