Adipose tissue may contribute to the development of many dangerous cancers, incl. breast, cervix and colon. This is the conclusion of an analysis of over 50 years of research into the relationship between obesity and cancer. How is it possible that our own fat cells can lead us to cancer?
To better understand the relationship between obesity and cancer, scientists at the University of Utah in S alt Lake City (USA) analyzed 20 studies conducted between 1946 and 2017 on the subject. The results of the analysis were published in the journal "Cancer Prevention Research".
Worth knowingThe number of patients withOBESITYis constantly growing worldwide. In Poland, almost 70 percent suffer from overweight and obesity. society. He provided such data in 2016. Food and Nutrition Institute in Warsaw. Obesithologists (obesity), i.e. specialists in obesity treatment, remind that obesity is not only in itself a complicated chronic disease. It also contributes to the development of many other serious diseases. Among them - up to 16 dangerous tumors.
How obesity contributes to cancer?
Researchers in Utah reviewed studies on the effects of adipose tissue development in breast cancer, endometrial cancer, esophageal cancer, colorectal cancer, prostate cancer, head and neck cancer. First of all, they show what has been known for a long time. Obesity can increase the risk of inflammation and negatively affects cell metabolism and interferes with the proper functioning of our entire immune system. Thus, obesity itself contributes to the so-called carcinogenesis, that is, the formation of tumors.
What is the "cancerous" effect of fat cells? First, some of them are more "metabolically active". That is, they produce more than any other substance that stimulates cancer cells to grow. Secondly, fat cells can penetrate directly into tumor sites and stimulate tumor cells to multiply. Such cells are most common in obese women who develop breast cancer and in obese men and prostate cancer.
Third, cancer development can also be influenced by the type of fatty tissue and where it accumulates. It turned out that each of the three types of tissue - white, brown and beige - is present in different amounts andit behaves differently depending on where it is located. For example, in colorectal cancer, adipose tissue is usually adjacent to the tumor, and in breast cancer, it is part of the tumor's microenvironment.
This is not the end of cancer and OBESITY research
A research meta-analysis conducted by American scientists allowed for a better understanding of the mechanisms of cancer formation in people with obesity. However, they encourage research centers to carry out more detailed research into the relationship between the location of adipose tissue and types of cancer. Maybe in this way we will discover ways to inhibit carcinogenic processes in obese patients?
Based on the article from: www.onkologia.esculap.com
ImportantPoradnikzdrowie.pl supports safe treatment and a dignified life of people suffering from obesity.
This article does not contain discriminatory and stigmatizing content for people suffering from obesity.
Magdalena Gajda
Obesity disease specialist and obesity discrimination among people. President of the Obesity Patients Foundation OD-WAGA, Social Ombudsman for the Rights of People with Obesity in Poland and a representative of Poland in the Obesity Patient Council of the European Society for Obesity Research. By profession - a journalist specializing in he alth matters. Privately - she has been obese since childhood, after bariatric surgery in 2010. Initial weight - 136 kg, current weight - 78 kg.
Based on the article from: www.onkologia.esculap.com
OD-WAGA Foundation