VERIFIED CONTENTAuthor: Karolina Porowska

Lorazepam is an organic chemical compound. Belongs to psychotropic drugs from the benzodiazepine group. The drug has anxiolytic and hypnotic properties. He was discovered by D.J. Richards and introduced to the US market in 1977 by Wyeth Pharmaceuticals. In 1985, it was used to treat anxiety disorders by the FDA. Lorazepam can be purchased with a prescription in the form of tablets.

Composition of lorafen

Tablet (Lorafen, 1 mg sugar-coated tablets)contains the active ingredient: lorazepam (Lorazepamum); excipients: potato starch, sodium carboxymethyl starch (type A), gelatin, talc, magnesium stearate, lactose monohydrate, polyvinyl alcohol, talc, m altodextrin, sucrose, titanium dioxide, opaglos 6000.

Tablet (Lorafen, 2.5 mg coated tablets)contains the active ingredient: lorazepam (Lorazepamum); excipients: potato starch, sodium carboxymethyl starch (type A), gelatin, talc, cochineal red (E-124), magnesium stearate, lactose monohydrate, polyvinyl alcohol, talc, m altodextrin, sucrose, cochineal red lake (E-124), opaglos 6000 , titanium dioxide.

Action of lorafen

Lorazepam has an anxiolytic, hypnotic, anticonvulsant and muscle relaxing effect.

The mechanism of action is based on exerting an influence on the central nervous system, especially the GABA-ergo system, through connection with the GABA-A receptor.

This sensitizes this receptor to the action of g-aminobutyric acid (GABA), which is the most important inhibitory amino acid in the central nervous system (CNS).

Application of lorafen

Lorazepam is used in the treatment of anxiety disorders, in reducing preoperative anxiety, in relieving symptoms such as anxiety and anxiety in depression.

Indications for the use of lorafen

It is recommended to use the drug in anxiety disorders of various origins, accompanying cardiovascular diseases, gastrointestinal diseases, in sleep disorders related to states of increased anxiety.

Contraindications to the use of lorafen

Do not use the drug if you are allergic to lorazap or to any of the modules listed in the drug. Not recommendeduse the drug when the patient is struggling with severe respiratory failure, lung diseases, night apnea syndrome, severe liver failure and kidney failure.

The drug is also contraindicated in severe liver failure and myasthenia gravis.

Lorafen dosage

The drug should be used as described in the patient information leaflet or according to specific guidelines and recommendations of a doctor or pharmacist. Check with your doctor or pharmacist if you are not sure.

Precautions

When using the drug, special care should be taken in elderly patients with weakened chronic respiratory disorders, with hepatic and renal failure, seizures, narrow-angle glaucoma, acute porphyria, alcohol intoxication, drugs or drugs that act on the central nervous system.

Prolonged use of the drug, at least for several weeks, may lead to decreased efficacy or mental and physical dependence. The drug may induce anterograde amnesia, which may occur after the administration of therapeutic doses.

Side effects of lorafen

Lorazepam can cause:

  • dizziness,
  • sleepiness,
  • lethargy,
  • headache,
  • ataxia,
  • slurred speech,
  • forgetting,
  • confusion,
  • confusion,
  • disclosure of depression,
  • dizziness,
  • muscle weakness,
  • asthenia,
  • reduce vigilance,
  • suppress emotions,
  • visual disturbance (including double vision and blurred vision),
  • nausea,
  • gastrointestinal complaints,
  • change in appetite,
  • skin reactions,
  • libido change,
  • impotence,
  • orgasm weakening and others.

Interaction with other drugs and diseases

In order to avoid undesirable ailments, inform your doctor or pharmacist about all medications that are currently or recently used, as well as about medications that the patient is going to use.

You should also inform your doctor about your current he alth condition, about any diseases or additional ailments you are struggling with.

Drugs that should not be combined with lorazepam include :

  • drugs that depress the central nervous system,
  • antiepileptic drugs,
  • drugs used in addiction treatment,
  • drugs used to treat disorders of the gastrointestinal tract,
  • antibiotics,
  • muscle relaxants,
  • Asthma medications,
  • antihypertensive drugs,
  • vasodilator,
  • diuretics,
  • narcotic painkillers or oral contraceptives.

Pregnancy and breastfeeding

Before taking the drug, inform your doctor if you are pregnant or breastfeeding. The use of lorazepam is generally not recommended in pregnant women and during breastfeeding.

Storing medicine

The drug should be stored in a suitable place that is invisible and inaccessible to children. Store in a dry place below 25 ° C in the original packaging.

The drug should not be used after the expiry date stated on the package. The expiry date refers to the last day of that month.

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He alth