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Please let me know what are the beta-hCG standards at different stages of pregnancy? When to do the test, what concentration means pregnancy?

Human Chorionic Gonadotropin (hCG) is produced by trophoblast cells. It can be detected in the blood after blastocyst implantation, around 9-10 days after fertilization (fertilization of the egg is not synonymous with intercourse!).

Marking it in the first stage of pregnancy is used to detect pregnancy early, and repeat tests to assess the development of pregnancy. Lack of hCG increase in subsequent tests may be associated with death of the pregnancy or its incorrect location (ectopic pregnancy).

hCG is a glycoprotein hormone composed of two chains (subunits) of alpha and beta. The alpha subunit is identical to that of the TSH, LH and FSH hormones. The beta subunit is specific to hCG and therefore it is best to test it, not all of the hCG.

During pregnancy, hCG stimulates the proper development and function of the corpus luteum, and in the placenta it is involved in the synthesis of steroid hormones. The concentration of hCG increases rapidly from the beginning of pregnancy, peaking between 9 and 12 weeks of pregnancy, then decreases, and from around 20 weeks of gestation it remains constant at around 20% of the maximum concentration.

The range of norms for individual weeks of pregnancy is always provided on each test result for this hormone, because it depends on the method of determination and may differ between laboratories.

Remember that our expert's answer is informative and will not replace a visit to the doctor.

Barbara Grzechocińska

Assistant professor at the Department of Obstetrics and Gynecology at the Medical University of Warsaw. I accept privately in Warsaw at ul. Krasińskiego 16 m 50 (registration is available every day from 8 a.m. to 8 p.m.).

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