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I have hypothyroidism and Hashimoto's disease. I have been taking Letrox 100 for several years. In May I had an appointment with an endocrinologist and it turned out that my TSH=5.08 (the norm is 0.27 to 4.2). The endocrinologist increased the dose of Letrox to 125. I am worried that I am planning a pregnancy and that increasing the dose of Letrox from 100 to 125 will not lower my TSH to below 2.00 (which I must have during pregnancy). I only heard from the endocrinologist that I should come in the 12th week of pregnancy, then the dose of the drug will probably need to be increased. I plan my pregnancy in a few months, how often I should do TSH tests, because my next visit is in a year. To what level should TSH fall before pregnancy and what may be the risk of a baby with hypothyroidism?
The optimal TSH concentration before a planned pregnancy is 2.5 mIU / l. After a dose change, another test should be performed after at least 4-6 weeks.
The effect of hypothyroidism on fetal development depends on whether it is latent (normal fT4) or overt hypothyroidism. In the case of latent, according to the latest research results, the development of the fetus is normal, in the case of overt hypothyroidism, neurological development disorders of the child may occur.
Remember that our expert's answer is informative and will not replace a visit to the doctor.
Barbara GrzechocińskaAssistant professor at the Department of Obstetrics and Gynecology at the Medical University of Warsaw. I accept privately in Warsaw at ul. Krasińskiego 16 m 50 (registration is available every day from 8 a.m. to 8 p.m.).
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