A new mixed vaccination scheme against COVID-19 has been in force since January 3. The scheme has been updated in accordance with the latest guidelines of the Medical Council, based on the positions of the EMA, FDA and ECDC, and the changes concern the schedules for vaccination with Moderna, Pfiizer / BioNTech, AstraZeneca and Johnson & Johnson preparations.
The announcement on this matter appeared on the website of the Ministry of He alth. It states that the changes are introduced due to the "current recommendations of the Medical Council and the Immunization Team, based on the position of the European Medicines Agency (EMA) and the European Center for Disease Prevention and Control (ECDC) and the position of the US Food Agency. and Medicines (FDA) ".
Recommended schedule of primary vaccination against COVID-19 in adults
As reported by the Ministry of He alth, in the basic scheme for people over 18 years of age, in order to complete the initiated vaccination scheme with Spikevax (Moderna), Comirnaty (Pfizer-BioNTech), or Vaxzevria (AstraZeneca), when it is necessary to change the preparation the patient, for whatever reason, can be given any other available mRNA vaccine or Vaxzevria (AstraZeneca) vaccine with an interval equal to or greater than 28 days between doses.
The Ministry emphasizes that "The recommended basic scheme is still the homologous scheme with the use of one preparation, and in the case of mixed (heterologous) schemes, the following order is recommended: vector vaccine - mRNA vaccine".
As we read on the MZ website. the reverse mixed scheme can be implemented in the case of individual indications for such a procedure.
Recommended schedule of booster vaccinations for adults
In the case of booster vaccinations in people over 18 years of age, the ministry recommends administering the vaccine in appropriate dosing schedules:
- after vaccination with primary mRNA preparation or Vaxzevria (AstraZeneca) administration of mRNA vaccine at least 5 months apart,
- after vaccination with COVID-19 Vaccine Janssen vaccination with COVID-19 Vaccine Janssen or mRNA vaccine at least 2 months apart,
- A booster dose of Vaccine Janssen COVID-19 may be conditionally administeredas a heterologous booster dose following primary COVID-19 mRNA vaccination with an interval of at least 5 months after completion of the full COVID-19 vaccination regimen.
As outlined in the guidelines, vaccines may be used in those vaccinated with a booster dose:
- Pfizer Comirnaty full dose 0.3 ml
- Moderna Spikevax half dose: 50 µg - 0.25 ml
- Johnson & Johnson Vaccine Janssen in a full dose of 0.5 ml
taking into account the first use of the vaccine given in the basic vaccination schedule or the observance of the order of vaccination after the vector vaccine administration of the mRNA vaccine.