If both parents have blue eyes, can their child have brown eyes?

The answer to this question is more complicated than it would seem to anyone who remembers what was said in biology class at school. We used to present the problem in a simplified way, suggesting that eye color is determined by one gene and that the blue version of the gene is recessive. In such a "school" arrangement, if both parents had blue irises, they would have no chance of having a child with a different eye color.

Real eye color inheritance

In fact, eye color is determined by the amount of melanin (black pigment) and the ratio of eumelanin (dark brown pigment) to pheomelanin (reddish pigment). The OCA2 and HERC2 genes play the most important role in determining the color of the irises, but apart from those mentioned, there are at least 10 other genes known to influence this trait. Ultimately, the interaction of all these genes determines the final effect. Thus, blue-eyed parents can have brown-eyed children.

Remember that our expert's answer is informative and will not replace a visit to the doctor.

Krystyna Spodar

Krystyna Spodar - specialist in the field of clinical genetics at NZOZ Genomed, ul. Ponczowa 12, 02-971 Warsaw, www.nzoz.genomed.pl, e-mail: [email protected]

The expert answers questions about genetic diseases and congenital malformations, inheritance, and prenatal diagnosis.

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