Uric acid is one of the parameters of blood chemistry. The level of its concentration in the body is important, first of all, in the diagnosis of gout and kidney diseases. Check what are the norms of uric acid in the blood and what may be evidenced by its too high level.

Uric acidis the end product of the metabolism of purine bases, and its concentration depends on the rate of synthesis and excretion from the body.Blood chemistryfor uric acid levels is ordered when gout, kidney disease or proliferative diseases are suspected. Such a test is also performed in order to check the correctness and effectiveness of the treatment.

Uric acid - norms in a biochemical test

The normal uric acid level is3 - 7 mg / dl .

Blood uric acid level should be less than 6mg / dl in order not to adversely affect he alth.

However, in people at high cardiovascular risk, it should be even lower - less than 5 mg / dL.

Increase in uric acid concentration

An increase in uric acid in the blood means that the body produces more of it.

Symptoms of increased uric acid levels are:

  • fever,
  • joint pain,
  • nausea,
  • vomiting,
  • hematuria,
  • urine retention,
  • stomach pains,
  • pains in the lumbar spine.

Excessive increase in uric acid concentration(hyperuricemia) may be primary or secondary.

Primary hyporuricemiadevelops as a result of congenital defects in metabolism, such as Lesch-Nyhan syndrome (approximately 1 percent of cases) or impaired secretion in the renal tubules (99 percent of cases).

Causesecondary hyperuricemiacan be:

  • a high-protein diet that is rich in purines,
  • gout,
  • psoriasis,
  • tissue hypoxia,
  • large tissue damage, e.g. as a result of an accident or in the case of cancer - massive cell breakdown during chemotherapy,
  • kidney failure,
  • lead poisoning,
  • some medications.

The most common symptoms of hyperuricemia are:

  • gout with high fever,
  • renal colic.

How to lower uric acid levels?

Uric acid concentration can be lowered, among others by changing eating habits and diet. The most important thing is to hydrate the body. In case of elevated uric acid concentration, it is recommended to drink 2-3 liters of fluid a day. Water is the best solution, and you can also drink herbal teas.

You shouldn't eat:

  • strong teas,
  • coffee,
  • alcohol,
  • beverages with a lot of fructose,
  • fruit juices,
  • fatty foods,
  • dairy,
  • legumes,
  • excessive s alt.

Recommended products include :

  • fruit,
  • cereal products,
  • and lean meat (preferably poultry).

Uric acid concentration drop

A drop in uric acid is called hypouricemia. It may indicate a metabolic disorder.

Appears, for example, in xanthinuria (a rare genetic disorder treated by drinking plenty of fluids and avoiding foods rich in purines) or as a result of increased renal secretion, e.g. in SIADH, i.e. in Schwartz-Bartter syndrome ( incorrect release of vasopressin). It can also be a combination of both of these states.

Reduced uric acid concentration can also appear in:

  • Franconi's team,
  • liver diseases,
  • kidney disease,
  • Wilson's disease,
  • celiakii.
  • LDH (LD), lactate dehydrogenase - norms
  • Acid phosphatase (ACP) - standards in biochemical testing

Testing uric acid levels from blood or urine

In order to determine the level of uric acid, it is necessary to perform biochemical tests. They can be made from both the blood sample and the daily urine collection.

You should go to the test on an empty stomach, preferably in the morning. It involves drawing blood from a vein in the arm. In the case of urine testing, you should urinate into a special container immediately after waking up and deliver it to the laboratory.

  • Blood count: how to read the result
  • Blood morphology - what this blood test is about
  • Urinalysis - general analysis

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