Help the development of the site, sharing the article with friends!

Gliński-Simmonds disease is also referred to as hypopituitarism, pituitary cachexia or pituitary necrosis. Gliński-Simmonds disease is a chronic multi-glandular hypothyroidism. It leads to the destruction of the organism similar in symptoms to anorexia.


  1. Glinski-Simmonds disease - causes
  2. Glinski-Simmonds disease - symptoms
  3. Glinski-Simmonds disease - treatment

Glinski-Simmonds diseaseis caused by damage to the pituitary gland or the hypothalamus, leading to disturbances in secretory functions. The complete destruction of the pituitary gland leads to disorders of the proper functioning of the glands dependent on it, which may cause hypothyroidism, adrenal insufficiency, and impaired function of the ovaries.

Glinski-Simmonds disease - causes

Gliński-Simmonds disease is usually seen in women between the ages of 30 and 40, and may be caused by severe labor and postpartum hemorrhage, leading to ischemic pituitary necrosis. Injury to the anterior pituitary gland can also be caused by a tumor in this part of the brain, pituitary surgery, radiation therapy, head injuries, inflammation and infections, e.g. tuberculosis, syphilis, and meningitis. Sometimes pituitary insufficiency is caused by systemic diseases, e.g. leukemia, lymphoma, cerebral arteriosclerosis, malnutrition, as well as disorders of the immune system.

Glinski-Simmonds disease - symptoms

The accompanying symptoms depend on the degree of damage to the pituitary gland. Most often, the function responsible for a single group of hormones is disturbed, but there are situations when the secretory function is more disturbed. As a result of hypopituitarism, the following hormones may be deficient:

  • vasopressin
  • luteinizing hormone (stimulates the production of hormones in the sex glands)
  • growth hormone
  • thyroid stimulating hormone (regulating the thyroid gland)

Occasionally, postpartum pituitary necrosis causes a lack of prolactin in the obstetrician. Gliński-Simmonds disease maylead to decreased immunity, increased susceptibility to infections and infections. As a result of pituitary insufficiency, blood sugar levels drop, emaciation and emaciation, very similar to anorexia. Symptoms of the disease may also include drowsiness, libido disorders, loss of appetite, apathy, convulsions, increased intracranial pressure. In extreme cases, the patient may fall into a coma.

Glinski-Simmonds disease - treatment

The effectiveness of the treatment of pituitary cachexia depends on when it is detected. The sooner it is diagnosed, the better the chances of a good prognosis. Treatment consists in replenishing the loss of sex hormones, adrenal cortex and thyroid gland. In the case of the presence of a pituitary tumor, surgical treatment is applied.

About the authorMonika Majewska A journalist specializing in he alth issues, especially in the areas of medicine, he alth protection and he althy eating. Author of news, guides, interviews with experts and reports. Participant of the largest Polish National Medical Conference "Polish woman in Europe", organized by the "Journalists for He alth" Association, as well as specialist workshops and seminars for journalists organized by the Association.

Read more articles by this author

Help the development of the site, sharing the article with friends!