Researchers at George Washington University found that low doses of aspirin can reduce the need for mechanical ventilation, ICU admission, and hospital mortality in hospitalized COVID-19 patients. The results of the study were published in Anesthesia & Analgesia.
The study enrolled over 400 patients admitted to hospitals across the United States between March and July 2022, including GW Hospital, University of Maryland Medical Center, Wake Forest Baptist Medical Center, and Northeast Georgia He alth System.
Adjusted for demographics and comorbidities, the use of aspirin was associated with a reduction in the risk of mechanical ventilation (44% reduction), ICU admission (43% reduction), and in-hospital mortality (47% reduction).
There was no difference in major bleeding or overt thrombosis between aspirin users and non-aspirin users.
Use of aspirin in the course of COVID-19
"When we learned about the link between blood clots and COVID-19, we knew that aspirin - used to prevent stroke and heart attack - could be important for COVID-19 patients," said Dr. Jonathan Chow, assistant professor of anesthesiology and intensive care and director of the Critical Care Anesthesiology Fellowship at GW School of Medicine and He alth Sciences.
"Our research has shown a link between low-dose aspirin and COVID-19 severity reduction and death," he stressed.
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